Table 5 A modified version of the conclusion to the survey of solvent selection guides [57]

Recommended

Ethanol (4)^a

Water

1-Butanol

Ethyl acetate (2)^a

1-Butyl acetate

Isopropanol (1)^a

Isopropyl acetate

Anisole

Sulpholane

Inbetween recommended and problematic

Acetic acid (9)^a

Acetone

Ethylene glycol

Methanol (3)^a

Acetic anhydride

t-Butanol

Methyl acetate

MIBK

Benzyl alcohol

Cyclohexanone

MEK

Problematic

DMSO {12 %}^b

2-MeTHF

Acetonitrile (10)^a

PhCl {2 %}^b

DMPU

Heptane (5)^a

Methylcyclohexane

Toluene (7)^a

Xylene(s)

Inbetween problematic and hazardous

THF (6)^a

Formic acid

TBME

Cyclohexane

DCM (8)^a {48 %}^b

Pyridine

Hazardous

Triethylamine

1,4-Dioxane {0 %}^b

1,2-DME {6 %}^b

DMAc {12 %}^b

DMF {31 %}^b

Methoxyethanol

NMP {9 %}^b

Diisopropyl ether {7 %}^b

n-Hexane {14 %}^b

Pentane

Highly hazardous

Diethyl ether {3 %}^b

Benzene

Chloroform {2 %}^b

Carbon tetrachloride

1,2-DCE {4 %}^b

Nitromethane