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Table 4 Mutagenicity Index (MI) and Mutagenic Activity Ratio (MAR) with the TA100 test strains of S. typhimurium at 5μL/plate both with and without S9 metabolic activation for all PILs and selected precursors in this study

From: Assessing the mutagenicity of protic ionic liquids using the mini Ames test

Code TA 100   TA 100  
Mutagenicity Index (MI)   Mutagenic Activity Ratio (MAR)
  S9 S9
[DMEtA][OAc] 1.10 ± 0.02 1.13 ± 0.14 0.11 ± 0.003 0.15 ± 0.010
[DMEtA][Pr] 0.99 ± 0.08 1.45 ± 0.19 −0.01 ± 0.001 0.46 ± 0.220
[DMEtA][Hex] 0.07 ± 0.08 0.15 ± 0.03 −0.95 ± 0.149 −0.96 ± 0.091
[DMEtA][Oct]
[DMEtA][Gly] 0.74 ± 0.16 1.65 ± 0.10 −0.42 ± 0.024 0.35 ± 0.059
[DMEtA][Succ] 1.09 ± 0.05 0.99 ± 0.08 0.14 ± 0.003 −0.01 ± 0.001
[DMEtA][Cl] 1.11 ± 0.22 1.04 ± 0.08 0.15 ± 0.026 0.02 ± 0.003
[EMEtA][OAc] 0.95 ± 0.12 1.14 ± 0.05 −0.06 ± 0.003 0.16 ± 0.020
[DEEtA][OAc] 0.73 ± 0.06 0.74 ± 0.05 −0.69 ± 0.058 −0.64 ± 0.080
[BDEtA][OAc] 1.01 ± 0.10 1.30 ± 0.30 0.01 ± 0.001 0.32 ± 0.060
[MDEOMA][OAc] 1.09 ± 0.09 0.88 ± 0.33 0.09 ± 0.005 −0.09 ± 0.010
[MEtA][OAc] 0.96 ± 0.13 1.02 ± 0.22 −0.02 ± 0.002 0.01 ± 0.003
[DEtA][OAc] 0.68 ± 0.09 0.83 ± 0.06 −0.23 ± 0.037 −0.09 ± 0.011
[DEtA][Cl] 1.32 ± 0.09 1.11 ± 0.16 0.20 ± 0.009 0.06 ± 0.011
[DEOMA][OAc] 1.48 ± 0.10 0.85 ± 0.04 0.24 ± 0.028 −0.27 ± 0.025
[DEOMA][Cl] 1.21 ± 0.16 0.54 ± 0.11 0.14 ± 0.010 −0.85 ± 0.020
Diethanolamine 1.50 ± 0.17 0.51 ± 0.11 0.26 ± 0.032 −0.85 ± 0.217
N,N-dimethylethanolamine 0.66 ± 0.20 0.41 ± 0.08 −0.22 ± 0.052 −0.22 ± 0.048