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Table 3 Mutagenicity Index (MI) and Mutagenic Activity Ratio (MAR) with the TA98 test strains of S. typhimurium at 5μL/plate both with and without S9 metabolic activation for all PILs and selected precursors in this study

From: Assessing the mutagenicity of protic ionic liquids using the mini Ames test

PIL TA 98   TA98  
Mutagenicity Index (MI) Mutagenic Activity Ratio (MAR)
  S9 S9
[DMEtA][OAc] 0.95 ± 0.22 0.84 ± 0.43 −0.03 ± 0.008 −0.44 ± 0.144
[DMEtA][Pr] 0.59 ± 0.15 0.27 ± 0.17 −0.53 ± 0.094 −1.64 ± 1.126
[DMEtA][Hex] 0.23 ± 0.18 1.10 ± 0.26 −0.28 ± 0.193 0.06 ± 0.009
[DMEtA][Oct]
[DMEtA][Gly] 1.64 ± 0.15 0.52 ± 0.29 1.00 ± 0.149 −0.89 ± 0.181
[DMEtA][Succ] 0.82 ± 0.14 6.33 ± 2.50 −0.78 ± 0.084 1.78 ± 1.267
[DMEtA][Cl] 2.10 ± 0.26 0.56 ± 0.36 2.83 ± 0.237 −0.22 ± 0.151
[EMEtA][OAc] 0.95 ± 0.30 1.40 ± 0.46 −0.02 ± 0.004 0.33 ± 0.047
[DEEtA][OAc] 2.03 ± 0.08 3.05 ± 0.42 0.55 ± 0.015 2.39 ± 0.466
[BDEtA][OAc] 0.83 ± 0.21 1.00 ± 0.20 −0.18 ± 0.032 0.00 ± 0.000
[MDEOMA][OAc] 2.69 ± 0.87 0.63 ± 0.37 0.45 ± 0.161 −0.17 ± 0.084
[MEtA][OAc] 0.36 ± 0.39 0.90 ± 0.72 −0.15 ± 0.052 −0.06 ± 0.035
[DEtA][OAc] 0.88 ± 0.53 1.36 ± 0.62 −0.03 ± 0.010 0.22 ± 0.132
[DEtA][Cl] 1.00 ± 0.25 0.70 ± 0.69 0.00 ± 0.000 −0.17 ± 0.112
[DEOMA][OAc] 1.11 ± 0.35 1.30 ± 0.32 0.07 ± 0.031 0.50 ± 0.176
[DEOMA][Cl] 1.69 ± 0.67 0.96 ± 0.24 0.03 ± 0.010 −0.06 ± 0.016
Diethanolamine 0.48 ± 0.48 1.78 ± 0.54 −0.18 ± 0.083 0.39 ± 0.112
N,N-dimethylethanolamine 0.74 ± 0.46 0.17 ± 0.15 −0.32 ± 0.143 −1.94 ± 0.970