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Table 9 Synthesis of 5-alkynyl nucleoside analogues 88-91

From: Heck and Sonogashira couplings in aqueous media – application to unprotected nucleosides and nucleotides

Entry

R

Product

Yield (%) a

1

88

71

2

89

42

3

90

55

4

91

84

  1. aAverage isolated yield from two or more trials.