Skip to main content

Table 9 Synthesis of 5-alkynyl nucleoside analogues 88-91

From: Heck and Sonogashira couplings in aqueous media – application to unprotected nucleosides and nucleotides

Entry R Product Yield (%) a
1 88 71
2 89 42
3 90 55
4 91 84
  1. aAverage isolated yield from two or more trials.