Skip to main content

Table 4 Synthesis of various 5-acrylate-2ʹ-deoxuridine analogues 7, 41-49

From: Heck and Sonogashira couplings in aqueous media – application to unprotected nucleosides and nucleotides

Entry Acrylate Product Yield (%)
1 32 90
2 33 90
3 4 45
4 34 45
5 35 45
6 36 40
7 37 45
8 38 35
9 39 60
10 40 51