Sustainable Chemical Processes

Table 3 Novel analogues of compound 4

From: Improved one-pot synthesis of N, N-diisopropyl-3-(2-Hydroxy-5-methylphenyl)-3-phenyl propanamide; a key intermediate for the preparation of racemic Tolterodine

Entrty	Coumarin	Amine	Product	Melting range	Yield
4		DIPA		169- 173°C (literature mp 170-173°C)⁷	75%
4a		DIPA		151-155°C	77%
4b		DIPA		168-172°C	73%
4c		DIPA		169-173°C	75%

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