From: Facile approach for the synthesis of rivaroxaban using alternate synthon: reaction, crystallization and isolation in single pot to achieve desired yield, quality and crystal form
Sr. no.
Solvent content by GC-HS in ppm
HPLC purity (%)
Yield (%)
DMSO
Acetonitrile
Methanol
1
9
11
14
15
1,068
238
352
99.81
0.01
ND
0.02
85.2
2
991
226
368
0.03
85.3
3
969
241
407
99.83
85.9