Expt. no. | DMSO (Vola) | ACN (Vola) | MeOH (Vola) | Yield (%) | Content by HPLC (%) | ACN content by GC (ppm) | ||||
---|---|---|---|---|---|---|---|---|---|---|
1 | 14 | 15 | NP | 11 | ||||||
1 | 5 | 10 | – | 69.1 | 99.85 | 0.06 | 0.03 | 0.02 | ND | 1,980 |
2 | 3 | 8 | – | 75 | 99.86 | 0.07 | 0.02 | 0.02 | ND | 753 |
3 | 4 | 10 | – | 71 | 99.51 | ND | 0.14 | ND | ND | NA |
4 | 4 | 6 | 4 | 71 | 99.51 | 0.15 | 0.03 | ND | ND | 580 |
5 | 4 | 4 | 6 | 75.0 | 99.56 | 0.06 | ND | ND | ND | 256 |
6 | 4 | 6 | 4 | 75.1 | 99.72 | 0.12 | ND | 0.02 | ND | NA |
7 | 4 | 6 | 9 | 80.2 | 99.68 | 0.05 | ND | 0.05 | ND | 337 |
8 | 4 | 4 | 6 | 87 | 99.79 | 0.04 | 0.03 | 0.03 | ND | 424 |
9 | 4 | 4 | 4 | – | 99.55 | 0.06 | ND | 0.01 | ND | 371 |
10 | 4 | 2 | 6 | – | 99.68 | 0.05 | 0.04 | ND | ND | 283 |
11 | 6 | 2 | 6 | 86.4 | 99.81 | 0.04 | ND | 0.04 | ND | 110 |
12 | 6 | 2 | 6 | 84.2 | 99.84 | 0.03 | 0.02 | ND | ND | 135 |